Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/NC/Hickory
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Hickory, NC

Studies commonly pay $75 to $4,500 per completed study

89 clinical trials are currently recruiting participants within 30 miles of Hickory. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

89studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Hickory right now

Top 25 of 89 recruiting studies, sorted by proximity — each links to its official registry page

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8 Phase 3 Interventional 474 participants sought
Novant Health Cancer Institute - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05624996)

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease, Overweight Phase 3 Interventional 12,800 participants sought
Burke Primary Care Family Practice — Morganton, North Carolina (20.3 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037433)

Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8 Phase 1, Phase 2 Interventional 92 participants sought
Wake Forest Baptist Health - Wilkes Medical Center — Wilkesboro, North Carolina (29.4 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04172532)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction Phase 3 Interventional 5,056 participants sought
Accellacare of Piedmont Healthcare — Statesville, North Carolina (24.6 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT07037459)

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 Phase 3 Interventional 1,524 participants sought
Novant Health Cancer Institute - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06876714)

Mobile Health for Adherence in Breast Cancer Patients

Anatomic Stage IV Breast Cancer AJCC v8, Breast Carcinoma N/A Interventional 410 participants sought
CaroMont Health - Lincoln Cancer Center — Lincolnton, North Carolina (18.9 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT06112613)

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Prostate Cancer (Adenocarcinoma) Phase 3 Interventional 830 participants sought
Atrium Health Lincoln/LCI-Lincolnton — Lincolnton, North Carolina (18.9 mi) · Sponsor: Canadian Cancer Trials Group
See eligibility & contact on ClinicalTrials.gov (NCT06592924)

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Obesity, Heart Failure Phase 3 Interventional 5,610 participants sought
IMA Research — Lenoir, North Carolina (17.0 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07567001)

A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence

Narcolepsy Type 1, Narcolepsy Type 2 Phase 2, Phase 3 Interventional 222 participants sought
Denver, North Carolina — Denver, North Carolina (21.9 mi) · Sponsor: Centessa Pharmaceuticals (UK) Limited
See eligibility & contact on ClinicalTrials.gov (NCT07598708)

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD Phase 3 Interventional 284 participants sought
Adverum Clinical Site 220 — Hickory, North Carolina (1.2 mi) · Sponsor: Adverum Biotechnologies, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07482176)

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis Phase 3 Interventional 2,150 participants sought
Akero Clinical Study Site — Statesville, North Carolina (24.6 mi) · Sponsor: Akero Therapeutics, Inc
See eligibility & contact on ClinicalTrials.gov (NCT06528314)

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Breast Cancer, NOS, CNS Primary Tumor, NOS N/A Interventional 400 participants sought
CaroMont Health - Lincoln Cancer Center — Lincolnton, North Carolina (18.9 mi) · Sponsor: Eastern Cooperative Oncology Group
See eligibility & contact on ClinicalTrials.gov (NCT05108298)

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Depressive Disorder, Major Phase 3 Interventional 752 participants sought
IMA Clinical Research PC 3 — Hickory, North Carolina (1.2 mi) · Sponsor: Janssen Research & Development, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06559306)

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma Phase 2, Phase 3 Interventional 138 participants sought
Atrium Health Lincoln/LCI-Lincolnton — Lincolnton, North Carolina (18.9 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT04402788)

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 Phase 2 Interventional 240 participants sought
Wake Forest Baptist Health - Wilkes Medical Center — Wilkesboro, North Carolina (29.4 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05327686)

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2 Phase 2 Interventional 270 participants sought
Piedmont Healthcare Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: Novo Nordisk A/S
See eligibility & contact on ClinicalTrials.gov (NCT07415954)

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Schizophrenia Phase 3 Interventional 280 participants sought
Local Institution - 176 — Hickory, North Carolina (1.2 mi) · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See eligibility & contact on ClinicalTrials.gov (NCT05304767)

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Chronic Idiopathic Constipation (CIC) Phase 3 Interventional 692 participants sought
Accellacare of Piedmont HealthCare — Statesville, North Carolina (24.6 mi) · Sponsor: Ardelyx
See eligibility & contact on ClinicalTrials.gov (NCT07382167)

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

Stage I Breast Cancer Phase 3 Interventional 1,670 participants sought
Novant Health Cancer Institute - Statesville — Statesville, North Carolina (24.6 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT04852887)

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Atrial Fibrillation (AF) Phase 3 Interventional 2,500 participants sought
Anthos Investigative Site 1001 — Lenoir, North Carolina (17.0 mi) · Sponsor: Anthos Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT05712200)

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

High Risk Cardiovascular Disease, Hypertension Phase 3 Interventional 11,000 participants sought
Clinical Trial Site — Statesville, North Carolina (24.6 mi) · Sponsor: Alnylam Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07181109)

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

Colorectal Cancer, Sarcopenia N/A Observational 300 participants sought
Wake Forest Baptist Health - Wilkes Medical Center — Wilkesboro, North Carolina (29.4 mi) · Sponsor: Wake Forest University Health Sciences
See eligibility & contact on ClinicalTrials.gov (NCT03998202)

A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

Acute Treatment of Migraine Phase 1 Interventional 16 participants sought
Accellacare - Piedmont — Statesville, North Carolina (24.6 mi) · Sponsor: Pfizer
See eligibility & contact on ClinicalTrials.gov (NCT06995729)

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma Phase 3 Interventional 382 participants sought
Wake Forest Baptist Health - Wilkes Medical Center — Wilkesboro, North Carolina (29.4 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05677490)
Actively enrolling

Studies you may be able to join near Hickory

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Hickory

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

PMG Research of Hickory

★ 5.0
221 13th Ave Pl NW Unit 201, Hickory, NC 28601
(828) 345-5060
"A great staff with innovative research team. Research group with new medicines tryed on volunteers. Why wait 20 years for approval of medicines? if q…"
— Donna r, 5★

IMA Clinical Research

★ 5.0
24 2nd Ave NE Ste 204, Hickory, NC 28601
(828) 322-3222
"Great place and the people there are very attentive to your concerns."
— Miguel Montoya, 5★

Clinical Trials of America

10 3rd Ave NE #400, Hickory, NC 28601
(828) 322-3222

Piedmont Endocrinology

★ 4.6
311 9th Ave Dr NE, Hickory, NC 28601
(828) 322-7338

Clinical Research of Gastonia

1010 X Ray Dr # A, Gastonia, NC 28054
(704) 675-7144

Rose Research Center

★ 4.9
8401 Medical Plaza Dr #275, Charlotte, NC 28262
(704) 350-2999
"I had an excellent experience I am definitely team Mary Beth and team rejoice definitely five stars for the ladies"
— Griselda Crawford, 5★

DelRicht Research | Charlotte Clinical Trials

★ 4.8
6719 Fairview Rd Ste A, Charlotte, NC 28210
(704) 644-8469
"The team members are kind and considerate. They will answer questions and provide you with feedback you can share with your primary provider. Super P…"
— Kenya Davis, 5★

Queen City Clinical Research, PLLC

330 Billingsley Rd Ste 206?, Charlotte, NC 28211
(704) 405-3150

New Hope Clinical Research, Inc.

★ 4.2
3101 Latrobe Dr, Charlotte, NC 28211
(980) 209-9784
"They called to screen me and I’m not even depressed. Just lied because I need the money. I’m sure they haven’t called a bunch of others like they cal…"
— Pluto Enterprises LLC, 3★

Clinical trials in Hickory: what's recruiting

The Hickory area currently has 89 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Hickory, the most active research areas are:

  • Cancer & Oncology12 studies
  • Heart & Vascular5 studies
  • Diabetes & Metabolism5 studies
  • Brain & Mental Health3 studies
  • Liver & Kidney2 studies

Every listing shows the study phase, the recruiting site and its distance from Hickory, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Hickory

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Hickory participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Hickory pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Are clinical trials in Hickory safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Hickory, NC?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
Is compensation for clinical trials taxable?
In the U.S., clinical trial compensation is generally considered taxable income, and research sites may issue a 1099 form for payments above $600 in a year. Reimbursements for travel or meals are typically treated differently. Consult a tax professional for your situation.
Can I be in more than one clinical trial at a time?
Generally no — most studies exclude participants currently enrolled in another trial, and paid Phase 1 studies enforce a washout period (often 30 days or more) between studies. Frequent healthy volunteers in Hickory typically complete one or two studies per year.

Paid clinical trials near Hickory

Other metros within reach

Gastonia, NC651 Charlotte, NC648 Concord, NC627 Rock Hill, SC585 Spartanburg, SC357 Winston-Salem, NC597 Asheville, NC120 High Point, NC597

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Hickory Bladder Issues Due To Spinal Cord Injury in Hickory All conditions

More of NC

Durham1,679 Cary1,679 Raleigh1,671 Burlington759 Gastonia651 Charlotte648 Concord627 High Point597 Winston-Salem597 Greensboro596 Asheville120 Fayetteville119

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