Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/KY/Lexington
Updated November 2026 from ClinicalTrials.gov

Paid Clinical Trials in Lexington, KY

Studies commonly pay $75 to $4,500 per completed study

479 clinical trials are currently recruiting participants within 30 miles of Lexington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

479studies recruiting
9+research centers nearby
4condition categories
Live from the NIH registry

Studies recruiting near Lexington right now

Top 25 of 479 recruiting studies, sorted by proximity — each links to its official registry page

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

Complex Congenital Heart Defect, Dysfunctional RVOT Conduit N/A Interventional 108 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Edwards Lifesciences
See eligibility & contact on ClinicalTrials.gov (NCT02744677)

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

Generalized Myasthenia Gravis N/A Observational 500 participants sought
Clinical Trial Site — Lexington, Kentucky (3.8 mi) · Sponsor: Alexion Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04202341)

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

Post Operative Surgical Site Infection Phase 3 Interventional 600 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Major Extremity Trauma Research Consortium
See eligibility & contact on ClinicalTrials.gov (NCT04678154)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Retina Associates of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

GENOCARE: A Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care

Colorectal Cancer, Pancreatic Cancer N/A Interventional 178 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Reema A. Patel
See eligibility & contact on ClinicalTrials.gov (NCT05391126)

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Antineutrophil Cytoplasmic Antibody-associated Vasculitis Phase 4 Interventional 300 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Amgen
See eligibility & contact on ClinicalTrials.gov (NCT06072482)

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Limited Stage Small Cell Lung Cancer Phase 2 Interventional 250 participants sought
Baptist Health - Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: SCRI Development Innovations, LLC
See eligibility & contact on ClinicalTrials.gov (NCT06773910)

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

Breast Cancer Phase 3 Interventional 450 participants sought
Baptist Health Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: Hoffmann-La Roche
See eligibility & contact on ClinicalTrials.gov (NCT06790693)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Lexington, Kentucky (3.8 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Saint Joseph Hospital — Lexington, Kentucky (3.8 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
University of Kentucky Markey Cancer Center ( Site 0019) — Lexington, Kentucky (3.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Cigarette Smoking-Related Carcinoma Phase 3 Interventional 600 participants sought
CommonSpirit Saint Joseph Hospital - Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: Alliance for Clinical Trials in Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05008848)

Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment

Lung Cancer N/A Interventional 234 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Laurie McLouth
See eligibility & contact on ClinicalTrials.gov (NCT06047301)

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis, Multiple Sclerosis N/A Observational 2,000 participants sought
TG Therapeutics Investigational Trial Site — Lexington, Kentucky (3.8 mi) · Sponsor: TG Therapeutics, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT06433752)

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

Clinical Stage IA Cutaneous Melanoma AJCC v8, Clinical Stage IB Cutaneous Melanoma AJCC v8 N/A Interventional 1,000 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: OHSU Knight Cancer Institute
See eligibility & contact on ClinicalTrials.gov (NCT06673095)

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

Atrial Fibrillation (AF) N/A Interventional 423 participants sought
Baptist Health Lexignton — Lexington, Kentucky (3.8 mi) · Sponsor: Vektor Medical
See eligibility & contact on ClinicalTrials.gov (NCT06935591)

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) Phase 3 Interventional 1,300 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Kura Oncology, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07007312)

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer, c-MET Phase 3 Interventional 768 participants sought
Baptist Health Lexington /ID# 252769 — Lexington, Kentucky (3.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT04928846)

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8 Phase 3 Interventional 1,500 participants sought
Saint Joseph Hospital — Lexington, Kentucky (3.8 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT05946213)

Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study

Spinal Cord Stimulation, Electric Stimulation Therapy N/A Interventional 30 participants sought
University of Kentucky - Chandler Medical Center — Lexington, Kentucky (3.8 mi) · Sponsor: Francis Farhadi
See eligibility & contact on ClinicalTrials.gov (NCT06520020)
Actively enrolling

Studies you may be able to join near Lexington

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

See which clinical studies you may qualify for

A partner research network matches volunteers with studies that are currently enrolling in the United States. You answer a few screening questions about your health and where you live; if a study looks like a fit, its team contacts you to confirm eligibility.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Lexington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Baptist Health Lexington Clinical Research Center

★ 5.0
1740 Nicholasville Rd, Lexington, KY 40503
(859) 260-3720

UK Center for Clinical and Translational Science (CCTS)

800 Rose St Rm C300, Lexington, KY 40508
(859) 323-2615

Sports Medicine Research Institute

★ 3.0
720 Sports Center Dr, Lexington, KY 40506
(859) 323-9850

AMR - Lexington (Alliance for Multispecialty Research)

★ 4.4
3475 Richmond Rd 3rd Floor, Lexington, KY 40509
(859) 264-8999
"Participated in a study 2 weeks ago and could not have been treated more professionally. Atmosphere was beautiful, calm and welcoming. Staff was fri…"
— Victoria Duvall, 5★

UK Precision Medicine Clinic

800 Rose St Second Floor, Suite HX200, Room HX 235, Lexington, KY 40536
(859) 323-7372

Healthy Kentucky Research Building

★ 5.0
760 Press Ave, Lexington, KY 40508
(859) 323-6108

Kentucky Clinical Trials Network

2365 Harrodsburg Rd, Lexington, KY 40504
(859) 323-1109

University of Kentucky Research Foundation

Kinkead Hall, 201 Kinkead Hall, Lexington, KY 40508
(859) 257-8311

Institute for Biomedical Informatics (IBI) at the University of Kentucky

University of Kentucky, Institute for Biomedical Informatics, Multidisciplinary Science, 725 Rose St Building, suite 230, Lexington, KY 40536

Clinical trials in Lexington: what's recruiting

The Lexington area currently has 479 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Lexington, the most active research areas are:

  • Cancer & Oncology14 studies
  • Heart & Vascular2 studies
  • Lungs & Breathing1 studies
  • Brain & Mental Health1 studies

Every listing shows the study phase, the recruiting site and its distance from Lexington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Lexington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Lexington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Lexington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Lexington?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Lexington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Lexington, KY?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Lexington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Lexington.

Paid clinical trials near Lexington

Other metros within reach

Cincinnati, OH1,128 Louisville, KY559 Dayton, OH308 Huntington, WV55 Knoxville, TN236 Indianapolis, IN953 Columbus, OH1,359 Murfreesboro, TN84

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Lexington Bladder Issues Due To Spinal Cord Injury in Lexington All conditions

More of KY

Louisville559

New paid studies open every week

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