Data sourced from ClinicalTrials.gov (NIH registry) Updated weekly IRB-supervised studies only
Home/KY/Lexington
Updated August 2026 from ClinicalTrials.gov

Paid Clinical Trials in Lexington, KY

Studies commonly pay $75 to $4,500 per completed study

472 clinical trials are currently recruiting participants within 30 miles of Lexington. Listings below come straight from the official NIH registry, alongside the area's top-rated research centers with real Google reviews.

472studies recruiting
9+research centers nearby
5condition categories
Live from the NIH registry

Studies recruiting near Lexington right now

Top 25 of 472 recruiting studies, sorted by proximity — each links to its official registry page

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Previously Treated Non-Small Cell Lung Cancer Phase 2, Phase 3 Interventional 10,000 participants sought
Baptist Health Lexington — Lexington, Kentucky (3.8 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT03851445)

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Neovascular Age-related Macular Degeneration Phase 4 Interventional 188 participants sought
Retina Associates of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Genentech, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT04853251)

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia Phase 2 Interventional 222 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT06124157)

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Lymphoma, Large B-Cell, Diffuse Phase 2 Interventional 594 participants sought
Baptist Health Lexington ( Site 0127) — Lexington, Kentucky (3.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT06890884)

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma Phase 2 Interventional 40 participants sought
Ohio State University-Telemedicine — Lexington, Kentucky (3.8 mi) · Sponsor: Sameek Roychowdhury
See eligibility & contact on ClinicalTrials.gov (NCT06906562)

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Smoldering Plasma Cell Myeloma Phase 3 Interventional 288 participants sought
Saint Joseph Hospital — Lexington, Kentucky (3.8 mi) · Sponsor: ECOG-ACRIN Cancer Research Group
See eligibility & contact on ClinicalTrials.gov (NCT03937635)

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Carcinoma, Non-Small-Cell Lung Phase 1, Phase 2 Interventional 450 participants sought
University of Kentucky Markey Cancer Center ( Site 0019) — Lexington, Kentucky (3.8 mi) · Sponsor: Merck Sharp & Dohme LLC
See eligibility & contact on ClinicalTrials.gov (NCT04165070)

Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment

Lung Cancer N/A Interventional 234 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Laurie McLouth
See eligibility & contact on ClinicalTrials.gov (NCT06047301)

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

Acute Myeloid Leukemia (AML) Phase 3 Interventional 1,300 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Kura Oncology, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07007312)

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

Parkinson Disease Phase 2 Interventional 150 participants sought
Kentucky Neuroscience Institute (Site #213) — Lexington, Kentucky (3.8 mi) · Sponsor: Appello Pharmaceuticals, Inc.
See eligibility & contact on ClinicalTrials.gov (NCT07432958)

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Multiple conditions Phase 1 Interventional 46 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: National Cancer Institute (NCI)
See eligibility & contact on ClinicalTrials.gov (NCT05172245)

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

Epithelial Ovarian Cancer, Fallopian Tube Cancer Phase 2 Interventional 140 participants sought
Baptist Health Lexington /ID# 275218 — Lexington, Kentucky (3.8 mi) · Sponsor: AbbVie
See eligibility & contact on ClinicalTrials.gov (NCT06890338)

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Carcinoma, Transitional Cell, Urinary Bladder Neoplasms Phase 3 Interventional 450 participants sought
University of Kentucky Chandler Medical Center — Lexington, Kentucky (3.8 mi) · Sponsor: Eli Lilly and Company
See eligibility & contact on ClinicalTrials.gov (NCT07218380)

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

Extensive-stage Small Cell Lung Cancer (ES-SCLC) Phase 1, Phase 2 Interventional 80 participants sought
University of Kentucky — Lexington, Kentucky (3.8 mi) · Sponsor: Novartis Pharmaceuticals
See eligibility & contact on ClinicalTrials.gov (NCT07564401)

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Plasma Cell Myeloma Phase 3 Interventional 510 participants sought
Saint Joseph Hospital — Lexington, Kentucky (3.8 mi) · Sponsor: SWOG Cancer Research Network
See eligibility & contact on ClinicalTrials.gov (NCT05561387)

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

Heart Failure Phase 3 Interventional 1,500 participants sought
CON-10080, Lexington, KY — Lexington, Kentucky (3.8 mi) · Sponsor: Colorado Prevention Center
See eligibility & contact on ClinicalTrials.gov (NCT06024746)

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8 Phase 3 Interventional 356 participants sought
University of Kentucky/Markey Cancer Center — Lexington, Kentucky (3.8 mi) · Sponsor: NRG Oncology
See eligibility & contact on ClinicalTrials.gov (NCT06958328)
Actively enrolling

Studies you may be able to join near Lexington

These studies are recruiting through partner research networks. We may be paid a referral fee if you complete their screening form — this never changes what you pay (nothing) or the compensation the study offers you.

Research study for alcohol-related liver damage

Enrolling US adults aged 18 to 70 with alcohol-induced liver damage and a history of heavy drinking. Not open to people with a recent stroke, heart attack, dialysis, or who take blood thinners.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility

Research study for bladder problems after spinal cord injury

This study is enrolling US adults aged 18 to 75 living with chronic involuntary bladder leakage caused by a spinal cord injury, for research including investigational gene therapy approaches. The study team confirms eligibility and any compensation before enrollment.

Screening is free and takes a few minutes. Eligibility and any compensation are confirmed by the study team, not by this site.

Check your eligibility
Google-rated

Top-rated research centers in Lexington

Dedicated clinical research sites near you — with their real Google ratings, reviews and contact details

Baptist Health Lexington Clinical Research Center

★ 5.0
1740 Nicholasville Rd, Lexington, KY 40503
(859) 260-3720

UK Center for Clinical and Translational Science (CCTS)

800 Rose St Rm C300, Lexington, KY 40508
(859) 323-2615

Sports Medicine Research Institute

★ 3.0
720 Sports Center Dr, Lexington, KY 40506
(859) 323-9850

AMR - Lexington (Alliance for Multispecialty Research)

★ 4.4
3475 Richmond Rd 3rd Floor, Lexington, KY 40509
(859) 264-8999
"Participated in a study 2 weeks ago and could not have been treated more professionally. Atmosphere was beautiful, calm and welcoming. Staff was fri…"
— Victoria Duvall, 5★

UK Precision Medicine Clinic

800 Rose St Second Floor, Suite HX200, Room HX 235, Lexington, KY 40536
(859) 323-7372

Healthy Kentucky Research Building

★ 5.0
760 Press Ave, Lexington, KY 40508
(859) 323-6108

Kentucky Clinical Trials Network

2365 Harrodsburg Rd, Lexington, KY 40504
(859) 323-1109

University of Kentucky Research Foundation

Kinkead Hall, 201 Kinkead Hall, Lexington, KY 40508
(859) 257-8311

Institute for Biomedical Informatics (IBI) at the University of Kentucky

University of Kentucky, Institute for Biomedical Informatics, Multidisciplinary Science, 725 Rose St Building, suite 230, Lexington, KY 40536

Clinical trials in Lexington: what's recruiting

The Lexington area currently has 472 studies open to new participants, according to the ClinicalTrials.gov registry maintained by the U.S. National Institutes of Health. Among the studies closest to Lexington, the most active research areas are:

  • Cancer & Oncology17 studies
  • Heart & Vascular2 studies
  • Brain & Mental Health2 studies
  • Lungs & Breathing1 studies
  • Diabetes & Metabolism1 studies

Every listing shows the study phase, the recruiting site and its distance from Lexington, and links to the official registry page where eligibility criteria and study contacts are published. Compensation is set by each sponsor: industry surveys report typical payments of $75 to $4,500 per completed study, with short observational studies at the low end and multi-visit or overnight Phase 1 studies at the high end.

How to enroll in a paid study in Lexington

Start with a study whose condition matches your profile — or a healthy-volunteer study if you have no diagnosis. Contact the research site through the registry page, complete a short phone screen, then attend an in-person screening visit. If you qualify, the study team walks you through the informed consent document, which details every procedure, risk and payment before you commit. You can withdraw at any point, and enrollment is always free.

Lexington participants can also register with the dedicated research centers listed above — many maintain volunteer databases and call when a matching study opens — or sign up for our email alert below to hear when a new study starts recruiting within 30 miles of your ZIP code.

Frequently asked questions

How much do paid clinical trials in Lexington pay?
Compensation varies by study length, procedures and overnight stays. Industry surveys report typical payments from $75 to $4,500 per completed study, with simple observational studies at the low end and multi-week inpatient Phase 1 studies at the high end. Each listing's study team will confirm the exact amount before you enroll.
Do I need to be sick to join a clinical trial in Lexington?
No. Many studies recruit healthy volunteers, especially early-phase studies run at dedicated research centers. Others need participants diagnosed with a specific condition. Every trial lists its eligibility criteria — age range, condition, medications — and the study team screens you before enrollment.
Are clinical trials in Lexington safe?
Every trial on this page is registered on ClinicalTrials.gov, the official NIH registry, and is overseen by an Institutional Review Board (IRB). Before joining you receive an informed consent document detailing procedures, risks and compensation. Participation is voluntary and you can withdraw at any time.
How do I join a study in Lexington, KY?
Pick a study that matches your profile, contact the research site (or apply through the study links on this page), pass a phone pre-screen, then attend an in-person screening visit. If you qualify, you review and sign the informed consent and the study begins. The process typically takes 1-3 weeks.
How often do new paid studies open in Lexington?
Constantly — trials open and close enrollment every week. This page is refreshed weekly from the NIH registry. Join the email alert to be notified when a new study opens within 30 miles of Lexington.

Paid clinical trials near Lexington

Other metros within reach

Cincinnati, OH1,127 Louisville, KY566 Dayton, OH310 Huntington, WV57 Knoxville, TN231 Indianapolis, IN915 Columbus, OH1,345 Murfreesboro, TN77

By condition

Eligibility and exclusions, condition by condition

Alcoholic Liver Disease in Lexington Bladder Issues Due To Spinal Cord Injury in Lexington All conditions

More of KY

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New paid studies open every week

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